The usual screening procedure are two colonoscopies at a ten-year interval or occult blood tests (FITs) performed annually or bianually. Theses details may differ depending on the country. However, both services involve disadvantages: even though colonoscopies are very precise, they are rarely used, mainly due to the unpleasant procedure and lengthy intestinal cleansing. While occult blood tests are more widely accepted, they can only provide indirect evidence of disease and often only in later, bleeding stages.

The following figures illustrate the need for action based on data from germany:

Colorectal cancer originates from the genetic mutation of intestinal cells. These are continuously excreted through the stool and can be examined for tumour DNA using modern genetic diagnostic methods. ColoAlert analyses samples for the following tumour makers:

• KRAS-mutation
• BRAF-mutation
• total amount of human DNA
• occult blood

These tumour markers can be associated with the occurrence of cancer.

In a multicentric study, a total of 566 patients were examined simultaneously using the occult blood test, M2-PK test and ColoAlert. All methods were also compared with the colonoscopy.

With a sensitivity of 85% and a specificity of 92%, ColoAlert showed the most accurate test results among the non-invasive screening methods.

Data protection is always important - especially when it comes to health related data! That is why we are regularly checked for our data security through independent committees.

Your sample will be examined exclusively for the tumour markers indicated above, no further data will be collected.
Your test results will only be sent to you or, if requested, to your attending physician.